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Báo cáo y học: "Hypocellular acute myeloid leukemia with bone marrow necrosis in young patients: two case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hypocellular acute myeloid leukemia with bone marrow necrosis in young patients: two case reports | Journal of Medical Case Reports BioMed Central Open Access Case report Hypocellular acute myeloid leukemia with bone marrow necrosis in young patients two case reports Deepali Jain 1 Tejinder Singh1 and Naresh Kumar2 Address Department of Pathology Maulana Azad Medical College New Delhi 110002 India and 2Department of Medicine Maulana Azad Medical College New Delhi 110002 India Email Deepali Jain - deepalijain76@gmail.com Tejinder Singh - tsinghmamc@yahoo.com Naresh Kumar - nareshdr114@yahoo.com Corresponding author Published 26 January 2009 Received 19 March 2008 Journal of Medical Case Reports 2009 3 27 doi 10.1186 1752-1947-3-27 Accepted 26 January 2009 This article is available from http www.jmedicalcasereports.cOm content 3 l 27 2009 Jain et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Introduction Hypocellular variants of acute myeloid leukemia are very rare and almost always occur in old aged patients. In contrast hypocellular acute lymphoblastic leukemia usually occurs in children. Case presentation We report two Indian patients with hypocellular acute myeloid leukemia a 32-year-old woman and a 13-year-old boy. Interestingly one of the patients also showed bone marrow necrosis. Conclusion Hypocellular acute myeloid leukemia is a rare entity and can affect young individuals. It can be considered as a rare cause of bone marrow necrosis. Introduction The infrequent occurrence of hypocellularity at presentation of acute leukemia has been widely recognized. Hypocellular variants of acute leukemia almost always have a myeloid phenotype and usually develop secondary to radiation or chemotherapy 1 2 . They thus occur mainly in .