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Báo cáo y học: " Pericardial effusion as the only manifestation of infection with Francisella tularensis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pericardial effusion as the only manifestation of infection with Francisella tularensis: a case report | Journal of Medical Case Reports BioMed Central Open Access Pericardial effusion as the only manifestation of infection with Francisella tularensis a case report Cécile Landais1 Pierre-Yves Levy1 Gilbert Habib2 and Didier Raoult 1 Address 1Université de la Méditerranée Unité des Rickettsies CNRS UMR 6236 IRD 3R198 IFR 48 Faculté de Médecine Boulevard Jean Moulin 13385 Marseille cedex 05 France and 2Department of Cardiology Timone Hospital Marseille France Email Cécile Landais - franzhertzog@aol.com Pierre-Yves Levy-pierre-yves.levy@mail.ap-hm.fr Gilbert Habib - gilbert.habib@mail.ap-hm.fr Didier Raoult - didier.raoult@gmail.com Corresponding author Published 13 June 2008 Received 19 December 2007 Journal of Medical Case Reports 2008 2 206 doi l0.ll86 l752-l947-2-206 Accepted 13 June 2008 This article is available from http www.jmedicalcasereports.cOm content 2 l 206 2008 Landais et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Francisella tularensis a facultative intracellular Gram-negative bacterium has rarely been reported as an agent of pericarditis generally described as a complication of tularemia sepsis. F. tularensis is a fastidious organism that grows poorly on standard culture media and diagnosis is usually based on serological tests. However cross-reactions may occur. Western blotting allows the correct diagnosis. Case presentation A non-smoking 53-year-old woman was admitted to hospital with a large posterior pericardial effusion. Serological tests showed a seroconversion in antibody titers to F. tularensis IgG titer 400 and Legionella pneumophila IgG titer 512 . F. tularensis was identified by Western immunoblotting following cross-adsorption. The patient reported close contact with .