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Báo cáo y học: " Non-Hodgkin's lymphoma in a woman with adult-onset Still's disease: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Non-Hodgkin's lymphoma in a woman with adult-onset Still's disease: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access Non-Hodgkin s lymphoma in a woman with adult-onset Still s disease a case report Zaher K Otrock1 Hassan A Hatoum2 Imad W Uthman2 Ali TTaher2 Shahrazad Saab1 and Ali I Shamseddine 2 Address Department of Pathology and Laboratory American University of Beirut Medical Center Beirut Lebanon and 2Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon Email Zaher K Otrock - zaherotrock@hotmail.com Hassan A Hatoum - hh42@aub.edu.lb Imad W Uthman - iuthman@aub.edu.lb AliTTaher- ataher@aub.edu.lb Shahrazad Saab - ss95@aub.edu.lb Ali I Shamseddine - as04@aub.edu.lb Corresponding author Published 6 March 2008 Received 14 June 2007 Journal of Medical Case Reports 2008 2 73 doi 10.1186 1752-1947-2-73 Accepted 6 March 2008 This article is available from http www.jmedicalcasereports.cOm content 2 1 73 2008 Otrock et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Adult onset Still s disease is a chronic multisystemic inflammatory disorder characterized by high spiking fever polyarthralgia and rash. Lymphadenopathy is a prominent feature of adult onset Still s disease and is seen in about 65 of patients. Searching the medical literature using the MEDLINE database from January 1966 through November 2007 we could only find two reported cases of adult onset Still s disease that had progressed to lymphoma. Case presentation We describe a woman who was diagnosed with adult onset Still s disease and developed lymphoma 10 months after the onset of her symptoms. She initially presented with fever and arthritis of the knees ankles and shoulders along with a nonpruritic skin rash myalgia and weight loss. On physical .