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Báo cáo khoa học: "Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro | Virology Journal BioMed Central Research Antiviral activity of gliotoxin gentian violet and brilliant green against Nipah and Hendra virus in vitro Mohamad Aljofan1 4 Michael L Sganga2 Michael K Lo3 Christina L Rootes1 Matteo Porotto2 Adam G Meyer5 Simon Saubern5 Anne Moscona2 and Bruce A Mungall 1 2 Address Australian Animal Health Laboratory CSIRO Livestock Industries Geelong Australia - Departments of Pediatrics and of Microbiology and Immunology Weill Medical College of Cornell University New York NY USA 3Measles Mumps Rubella and Herpes virus Laboratory Branch Division of Viral Diseases Centers for Disease Control and Prevention Atlanta Georgia USA 4School of Veterinary Science The University of Queensland St Lucia Australia and 5CSIRO Molecular and Health Technologies Clayton Australia Email Mohamad Aljofan - Mohamad.Aljofan@csiro.au Michael L Sganga - michaelsganga@gmail.com Michael K Lo - mko2@cdc.gov Christina L Rootes - Chris.Rootes@csiro.au Matteo Porotto - map2028@med.cornell.edu Adam G Meyer - Adam.Meyer@csiro.au Simon Saubern - Simon.Saubern@csiro.au Anne Moscona - anm2047@med.cornell.edu Bruce A Mungall - bmungall@live.com Corresponding author Open Access Published 4 November 2009 Received 24 July 2009 Accepted 4 November 2009 Virology Journal 2009 6 187 doi 10.1186 1743-422X-6-187 This article is available from http www.virologyj.com content 6 1 187 2009 Aljofan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Using a recently described monolayer assay amenable to high throughput screening format for the identification of potential Nipah virus and Hendra virus antivirals we have partially screened a low molecular weight compound library 8 000 compounds directly against live virus .