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Báo cáo khoa học: "Identification and characterisation of a novel anti-viral peptide against avian influenza virus H9N"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Identification and characterisation of a novel anti-viral peptide against avian influenza virus H9N | Virology Journal BioMed Central Open Access Identification and characterisation of a novel anti-viral peptide against avian influenza virus H9N2 Mohamed Rajik1 Fatemeh Jahanshiri1 Abdul Rahman Omar2 3 Aini Ideris2 3 Sharifah Syed Hassan4 and Khatijah Yusoff 1 2 Address Department of Microbiology Faculty of Biotechnology and Biomolecular Sciences University Putra Malaysia UPM Serdang Selangor 43400 Malaysia institute of Bioscience University Putra Malaysia UPM Serdang Selangor 43400 Malaysia 3Faculty of Veterinary Medicine Universiti Putra Malaysia UPM Serdang Selangor 43400 Malaysia and 4School of Medicine and Health Sciences Monash University Sunway Campus Kuala Lumpur Malaysia Email Mohamed Rajik - mmdrajik@gmail.com Fatemeh Jahanshiri - f.jahanshiri@gmail.com Abdul Rahman Omar - aro@ibs.upm.edu.my Aini Ideris - aiini@admin.upm.edu.my Sharifah Syed Hassan - sharifah.syedhassan@med.monash.edu.my Khatijah Yusoff - kyusoff@biotech.upm.edu.my Corresponding author Published 5 June 2009 Received 26 February 2009 Accepted 5 June 2009 Virology Journal 2009 6 74 doi l0.ll86 l 743-422X-6-74 This article is available from http www.virologyj.cOm content 6 1 74 2009 Rajik et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Avian influenza viruses AIV cause high morbidity and mortality among the poultry worldwide. Their highly mutative nature often results in the emergence of drug resistant strains which have the potential of causing a pandemic. The virus has two immunologically important glycoproteins hemagglutinin HA neuraminidase NA and one ion channel protein M2 which are the most important targets for drug discovery on its surface. In order to identify a peptide-based virus inhibitor against any of these .