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Báo cáo hóa học: "Blood doping by cobalt. Should we measure cobalt in athletes?"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Blood doping by cobalt. Should we measure cobalt in athletes? | Journal of Occupational Medicine and Toxicology BioMed Central Open Access Hypothesis Blood doping by cobalt. Should we measure cobalt in athletes Giuseppe Lippi 1 Massimo Franchini2 and Gian Cesare Guidi1 Address 1Istituto di Chimica e Microscopia Clinica Dipartimento di Scienze Morfologico-Biomediche Università degli Studi di Verona Verona Italy and 2Servizio di Immunoematologia e Trasfusione Azienda Ospedaliera di Verona Verona Italy Email Giuseppe Lippi - ulippi@tin.it Massimo Franchini - mfranchini@univr.it Gian Cesare Guidi - giancesare.guidi@univr.it Corresponding author Published 24 July 2006 Received 01 April 2006 Journal of Occupational Medicine and Toxicology 2006 1 18 doi 10.1186 1745-6673-1-18 Accepted 24 July 2006 This article is available from http www.occup-med.com content 1 1 18 2006 Lippi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Blood doping is commonplace in competitive athletes who seek to enhance their aerobic performances through illicit techniques. Presentation of the hypothesis Cobalt a naturally-occurring element with properties similar to those of iron and nickel induces a marked and stable polycythemic response through a more efficient transcription of the erythropoietin gene. Testing the hypothesis Although little information is available so far on cobalt metabolism reference value ranges or supplementation in athletes there is emerging evidence that cobalt is used as a supplement and increased serum concentrations are occasionally observed in athletes. Therefore given the athlete s connatural inclination to experiment with innovative unfair and potentially unhealthy doping .