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báo cáo hóa học: " Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài:Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity | Journal of Occupational Medicine and Toxicology BioMed Central Open Access Review Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity Dirk W Lachenmeier Address Chemisches und Veterinaruntersuchungsamt CVUA Karlsruhe Weissenburger Strasse 3 D-76187 Karlsruhe Germany Email Dirk W Lachenmeier - Lachenmeier@web.de Published 13 November 2008 Received 5 September 2008 _ AA __J -r.AAAO 1AZ J . IA I iozin.li ZZT - oz Accepted 13 November 2008 Journal of Occupational Medicine and Toxicology 2008 3 26 doi l0.ll86 l745-6673-3-26 This article is available from http www.occup-med.com content 3 1 26 2008 Lachenmeier licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Ethanol is widely used in all kinds of products with direct exposure to the human skin e.g. medicinal products like hand disinfectants in occupational settings cosmetics like hairsprays or mouthwashes pharmaceutical preparations and many household products . Contradictory evidence about the safety of such topical applications of the alcohol can be found in the scientific literature yet an up-to-date risk assessment of ethanol application on the skin and inside the oral cavity is currently lacking. The first and foremost concerns of topical ethanol applications for public health are its carcinogenic effects as there is unambiguous evidence for the carcinogenicity of ethanol orally consumed in the form of alcoholic beverages. So far there is a lack of evidence to associate topical ethanol use with an increased risk of skin cancer. Limited and conflicting epidemiological evidence is available on the link between the use of ethanol in the oral cavity in the form of mouthwashes or mouthrinses and oral cancer. Some studies .