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báo cáo hóa học:" Comparison of prognostic scores and surgical approaches to treat spinal metastatic tumors: A review of 57 cases"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Comparison of prognostic scores and surgical approaches to treat spinal metastatic tumors: A review of 57 cases | Journal of Orthopaedic Surgery and Research BioMed Central Open Access Research article Comparison of prognostic scores and surgical approaches to treat spinal metastatic tumors A review of 57 cases Selcuk Yilmazlar Seref Dogan Basak Caner Alper Turkkan Ahmet Bekar and Ender Korfali Address Department of Neurosurgery School of Medicine Uludag University Gorukle Kampus Bursa 16059 Turkey Email Selcuk Yilmazlar - selsus@uludag.edu.tr Seref Dogan - serefdogan01@yahoo.com Basak Caner - basakcaner@yahoo.com AlperTurkkan - alperturkkan@hotmail.com Ahmet Bekar - abekar@uludag.edu.tr Ender Korfali - neurobur@uludag.edu.tr Corresponding author Published 28 August 2008 Received 21 January 2008 Journal of Orthopaedic Surgery and Research 2008 3 37 doi l0.ll86 l749-799X-3-37 Accepted 28 August 2008 This article is available from http www.josr-online.cOm content 3 1 37 2008 Yilmazlar et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Surgical treatment of metastatic spinal cord compression with or without neural deficit is controversial. Karnofsky and Tokuhashi scores have been proposed for prognosis of spinal metastasis. Here we conducted a retrospective analysis of Karnofsky and modified Tokuhashi scores in 57 consecutive patients undergoing surgery for secondary spinal metastases to evaluate the value of these scores in aiding decision making for surgery. Comparison of preoperative Karnofsky and modified Tokuhashi scores with the type of the surgical approach for each patient revealed that both scores not only reliably estimate life expectancy but also objectively improved surgical decisions. When the general status of the patient is poor i.e. Karnofsky score less than 40 or modified Tokuhashi score of 5 or greater .