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Báo cáo hóa học: " In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains | Virology Journal BioMed Central Short report Open Access In vitro permissivity of bovine cells for wild-type and vaccinal myxoma virus strains Beatrice Pignolet1 Jean-Luc Duteyrat1 3 Aude Allemandou1 3 Jacqueline Gelfi1 Gilles Foucras2 and Stephane Bertagnoli 1 Address Laboratory Interactions Hôtes-Virus et Vaccinologie UMR 1225 INRA-ENVT Ecole Nationale Vétérinaire de Toulouse 23 chemin des capelles Toulouse F-31076 France laboratory Résistome des ruminants UMR 1225 INRA-ENVT Ecole Nationale Vétérinaire de Toulouse 23 chemin des capelles Toulouse F-31076 France and 3Centre de Microscopie Electronique Appliquée à la Biologie Faculté de Médecine de Rangueil 133 route de Narbonne Toulouse F-31062 France Email Béatrice Pignolet - b.pignolet@envt.fr Jean-Luc Duteyrat - jlucduteyrat@yahoo.fr Aude Allemandou - aude.allemandou@wanadoo.fr Jacqueline Gelfi - j.gelfi@envt.fr Gilles Foucras - g.foucras@envt.fr Stéphane Bertagnoli - s.bertagnoli@envt.fr Corresponding author Published 27 September 2007 Received 7 August 2007 Accepted 27 September 2007 Virology Journal 2007 4 94 doi l0.ll86 l 743-422X-4-94 This article is available from http www.virologyj.cOm content 4 1 94 2007 Pignolet et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Myxoma virus MYXV a leporide-specific poxvirus represents an attractive candidate for the generation of safe non-replicative vaccine vector for non-host species. However there is very little information concerning infection of non-laboratory animals species cells with MYXV. In this study we investigated interactions between bovine cells and respectively a wild type strain T1 and a vaccinal strain SG33 of MYXV. We showed that bovine KOP-R BT and MDBK cell lines do not support MYXV production.