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Báo cáo hóa học: " Genetic characterisation of the recent foot-and-mouth disease virus subtype A/IRN/2005"

Tham khảo tài liệu 'báo cáo hóa học: " genetic characterisation of the recent foot-and-mouth disease virus subtype a/irn/2005"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | BioMed Central Virology Journal Open Access Genetic characterisation of the recent foot-and-mouth disease virus subtype A IRN 2005 Joern Klein1 Manzoor Hussain2 Munir Ahmad2 Preben Normann1 Muhammad Afzal3 and Soren Alexandersen 1 Address National Veterinary Institute Technical University of Denmark Lindholm DK-4771 Kalvehave Denmark 2Food and Agriculture Organization of the United Nations - Pakistan NARC Park Road PK-45500 Pakistan and 3Ministry of Food Agriculture Livestock Pakistan Livestock wing PK-44000 Pakistan Email Joern Klein - jkle@vet.dtu.dk Manzoor Hussain - Manzoor.Hussain@fao.org Munir Ahmad - munirmul@hotmail.com Preben Normann - pn@vet.dtu.dk Muhammad Afzal - muhammad.afzal@lddb.org.pk Soren Alexandersen - sax@vet.dtu.dk Corresponding author Published 15 November 2007 Received 9 October 2007 Accepted 15 November 2007 Virology Journal 2007 4 122 doi l0.ll86 l743-422X-4-l22 This article is available from http www.virologyj.com content 4 l l22 2007 Klein et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background According to the World Reference Laboratory for FMD a new subtype of FMDV serotype A was detected in Iran in 2005. This subtype was designated A IRN 2005 and rapidly spread throughout Iran and moved westwards into Saudi Arabia and Turkey where it was initially detected from August 2005 and subsequently caused major disease problems in the spring of 2006. The same subtype reached Jordan in 2007. As part of an ongoing project we have also detected this subtype in Pakistan with the first positive samples detected in April 2006. To characterise this subtype in detail we have sequenced and analysed the complete coding sequence of three subtype A IRN 2005 isolates collected in Pakistan in 2006