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báo cáo hóa học:" A retrospective study of risk factors for poor outcomes in methicillin-resistant staphylococcus aureus (MRSA) infection in surgical patients"

Tham khảo tài liệu 'báo cáo hóa học:" a retrospective study of risk factors for poor outcomes in methicillin-resistant staphylococcus aureus (mrsa) infection in surgical patients"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | Eseonu et al. Journal of Orthopaedic Surgery and Research 2011 6 25 http www.josr-online.eom content 6 1 25 JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH RESEARCH ARTICLE Open Access A retrospective study of risk factors for poor outcomes in methicillin-resistant staphylococcus aureus MRSA infection in surgical patients Kelechi C Eseonu1 Scott D Middleton1 and Chinyere C Eseonu2 Abstract Background Since its isolation Methicillin-resistant Staphlococcus aureus MRSA has become a major cause of hospital acquired infection HAI adverse patient outcome and overall resource utilisation. It is endemic in Scotland and widespread in Western hospitals. MRSA has been the subject of widespread media interest- a manifestation of concerns about sterile surgical techniques and hospital cleanliness. This study aimed to investigate patient outcome of MRSA infections over the last decade at a major orthopaedic trauma centre. The objective was to establish the association of variables such as patient age and inpatient residence against patient outcome in order to quantify significant relationships facilitating the evaluation of management strategies with an aim to improving patient outcomes and targeting high-risk procedures. Methods This is a retrospective study of the rates and outcomes of MRSA infection in orthopaedic trauma at the Royal Infirmary of Edinburgh. Data was collated using SPSS 14.0 for Windows R . Shapiro-Wilkes testing was performed to investigate the normality of continuous data sets e.g age . Data was analysed using both Chi-Squared and Fisher s exact tests in cases of expected values under 5 Results This study found significant associations between adverse patient outcome persistent deep infection osteomyelitis the necessity for revision surgery amputation and mortality and the following patient variables Length of inpatient stay immuno-compromise pre-admission residence in an institutional setting such as a residential nursing home and the number of antibiotics .