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báo cáo hóa học:" Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme | BioMed Central Journal of the International AIDS Society Open Access Quality of life and the impact of drug toxicities in a South African community-based antiretroviral programme Jennifer Pitt 1 Landon Myer2 3 and Robin Wood1 Address 1Desmond Tutu HIV Foundation Institute of Infectious Diseases and Molecular Medicine Cape Town South Africa 2Infectious Diseases Epidemiology Unit School of Public Health Family Medicine University of Cape Town Cape Town South Africa and 3Department of Epidemiology Mailman School of Public Health Columbia University New York NY USA Email Jennifer Pitt - jennifer.pitt@hiv-research.org.za Landon Myer - lmyer@cormack.uct.ac.za Robin Wood - robin.wood@hiv-research.org.za Corresponding author Published 24 April 2009 Received 3 November 2008 Journal of the International AIDS Society 2009 12 5 doi 10.1186 1758-2652-12-5 Accepted 24 April 2009 This article is available from http www.jiasociety.Org content 12 1 5 2009 Pitt et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The impact of highly active antiretroviral therapy HAART on health-related quality of life has been widely researched in the developed world but there are few data from sub-Saharan Africa where the vast majority of HIV-infected individuals live. This study examined health-related quality of life among HIV-positive individuals initiating HAART in Cape Town South Africa and explored the impact of HAART-related drug toxicities on quality of life. Methods Health-related quality of life was assessed using a standardised questionnaire the Medical Outcomes Survey Short Form 36. Physical health summary scores and mental health summary scores were compared pre-HAART and at regular intervals during the first 48 weeks of .