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Health and Quality of Life Outcomes BioMed Central Research Open Access Social function in

Health and Quality of Life Outcomes BioMed Central Research Open Access Social function in schizophrenia and schizoaffective disorder: Associations with personality, symptoms and neurocognition Paul H Lysaker*1,2 and Louanne W Davis1 Address: 1Roudebush VA Medical Center, Day Hospital 116H, 1481 West 10th St, Indianapolis, Indiana 46202, USA and 2Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA Email: Paul H Lysaker* - plysaker@iupui.edu; Louanne W Davis - louanne.davis@med.va.gov * Corresponding author Published: 16 March 2004 Health and Quality of Life Outcomes 2004, 2:15 This article is available from: http://www.hqlo.com/content/2/1/15 Received: 22 December 2003 Accepted: 16 March 2004 © 2004 Lysaker and Davis; licensee BioMed Central Ltd | BioMed Central Health and Quality of Life Outcomes Research Open Access Social function in schizophrenia and schizoaffective disorder Associations with personality symptoms and neurocognition Paul H Lysaker 1 2 and Louanne W Davis1 Address 1Roudebush VA Medical Center Day Hospital 116H 1481 West 10th St Indianapolis Indiana 46202 USA and 2Department of Psychiatry Indiana University School of Medicine Indianapolis Indiana 46202 USA Email Paul H Lysaker - plysaker@iupui.edu Louanne W Davis - louanne.davis@med.va.gov Corresponding author Published 16 March 2004 Received 22 December 2003 Accepted 16 March 2004 Health and Quality of Life Outcomes 2004 2 15 r This article is available from http www.hqlo.com content 2 l l5 2004 Lysaker and Davis licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background Research has indicated that stable individual differences in personality exist among persons with schizophrenia spectrum disorders predating illness onset that are linked to symptoms and self appraised quality of life. Less is known about how closely individual differences in personality are uniquely related to levels of social relationships a domain of dysfunction in schizophrenia more often linked in the literature with symptoms and neurocognitive deficits. This study tested the hypothesis that trait levels of personality as defined using the five-factor model of personality would be linked to social function in schizophrenia. Methods A self-report measure of the five factor model of personality was gathered along with ratings of social function symptoms and assessments of neurocognition for 65 participants with schizophrenia or schizoaffective disorder. Results Univariate correlations and stepwise multiple regression indicated that frequency of social interaction was predicted by .