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báo cáo hóa học:"Factors affecting the relationship between psychological status and quality of life in COPD patients"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài :Factors affecting the relationship between psychological status and quality of life in COPD patients | Balcells et al. Health and Quality of Life Outcomes 2010 8 108 http www.hqlo.eom content 8 1 108 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Factors affecting the relationship between psychological status and quality of life in COPD patients Eva Balcells1 2 3 Joaquim Gea1 2 3 4 Jaume Ferrer3 5 Ignasi Serra2 6 Mauricio Orozco-Levi1 2 3 4 Jordi de Batlle2 6 7 c 1 f D I r I z t I I 73 5 2 6 7 Ch V 11 Ch s I u- o L . r -4 II . -72 6 I s- f- I . LZ . h I A L . 4.2 4 6 7 11 I zd I c. r T r r I A f m r r I r 2 4 6 7 Esther Rodríguez Marta Benet David Donaire-González Josep M Antó Judith Garcia-Aymerich the PAC-CoPd Study Group Abstract Background This study aims to i evaluate the association between anxiety and depressive symptoms and health-related quality of life HRQoL and ii identify the effect modifiers of this relationship in patients with chronic obstructive pulmonary disease COPD . Methods A total of 337 clinically stable COPD patients answered the St. George s Respiratory Questionnaire SGRQ assessing HRQoL and the Hospital Anxiety and Depression Scale HADS . Socio-demographic information lung function and other clinical data were collected. Results Most patients 93 were male they had a mean SD age of 68 9 years and mild to very severe COPD post-bronchodilator FEV1 52 16 predicted . Multivariate analyses showed that anxiety depression or both conditions were associated with poor HRQoL for all SGRQ domains . The association between anxiety and total HRQoL score was 6.7 points higher indicating a worse HRQoL in current workers than in retired individuals. Estimates for patients with both anxiety and depression were 5.8 points lower in stage I-II than in stage III-IV COPD and 10.2 points higher in patients with other comorbidities than in those with only COPD. Conclusions This study shows a significant association between anxiety depression or both conditions and impaired HRQoL. Clinically relevant factors affecting the magnitude of this association .