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báo cáo hóa học:"Valuation of scleroderma and psoriatic arthritis health states by the general public"

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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài :Valuation of scleroderma and psoriatic arthritis health states by the general public | Khanna et al. Health and Quality of Life Outcomes 2010 8 112 http www.hqlo.eom content 8 1 112 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Valuation of scleroderma and psoriatic arthritis health states by the general public PiỈnocH k H nn 1 2Tr Ỉ XỈ Pror K3 Di 112 D k hsỉnnTỉ1 i i k r ll Pi 2 K l rlz I I Vi4 5 Drin Pi I Itỉ c2 6 7 Dinesn Kiidinid Iidcy riecii rujd r Kiidinid Robert M Kdpldn Mdrk n Likrndn Ron D ndys Shaari S Ginsburg1 4 Anthony C Leondrd5 Joel Tsevdt4 5 8 Abstract Objective Psoridtic drthritis PsA dnd sclerodermd SSc die chronic rheumdtic disorders with detrimentdl effects on hedlth-reldted qudlity of life. Our objective wds to dssess hedlth vdlues utilities from the general public for hedlth stdtes common to people with PsA dnd SSc for economic evdludtions. Methods Adult subjects from the general populdtion in d Midwestern city N 218 completed the SF-12 Hedlth Survey dnd computer-dssisted 0-100 rating scdle RS time trade-off TTO range 0.0-1.0 dnd stdnddrd gdmble SG range 0.0-1.0 utility dssessments for several hypotheticdl PsA dnd SSc hedlth stdtes. Results Subjects included 135 62 femdles 143 66 Cducdsidns dnd 62 28 Africdn-Americdns. The medn SD scores for the SF-12 Physicdl Component Summdry scdle were 52.9 8.3 dnd for the SF-12 Mentdl Component Summdry scdle were 49.0 9.1 close to populdtion norms. The medn RS TTO dnd SG scores for PsA hedlth stdtes vdried with severity rdnging from 20.2 to 63.7 14.4-20.3 for the RS 0.29 to 0.78 0.24-0.31 for the TTO dnd 0.48 to 0.82 0.24-0.34 for the SG. The medn RS TTO dnd SG scores for SSc hedlth stdtes were 25.3-69.7 15.2-16.3 for the RS 0.36-0.80 0.25-0.31 for the TTO dnd 0.50-0.81 0.26-0.32 for the SG depending on disedse severity. Conclusion Hedlth utilities for PsA dnd SSc hedlth stdtes ds dssessed from the general public reflect the severity of the disedses. These descriptive findings could hdve implicdtions regdrding compdrdtive effectiveness resedrch for tests dnd tredtments for PsA dnd

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