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Hypertriglyceridemia

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A healthy 45-year-old man is found on routine screening to have hypertriglyceridemia. He is a nonsmoker, has a reasonable diet, consumes one alcoholic drink per week, and exercises regularly. He takes no medications. His father died at the age of 55 years in an automobile accident; his mother is healthy at 67 years of age, and he has two healthy older brothers. His blood pressure is normal, his body-mass index (the weight in kilograms divided by the square of the height in meters) is 28, and his waist circumference is 96 cm. His fasting triglyceride level is 400 mg per deciliter, total cholesterol 230 mg deciliter, low-density.