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HANDBOOK OF CANCER MODELS WITH APPLICATIONS

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In the past 15 years, molecular biologists and geneticists have uncovered some of the most basic mechanisms by means of which normal stem cells in a certain organ or tissue develop into cancerous tumors. This biological knowledge serves as a basis for various models of carcinogenesis. Furthermore, in order for biological findings to be tested quantitatively against human epidemiological data and animal experimental data and in order to develop efficient diagnostic, controlling, curative and preventive strategies for cancer, it is essential that these biological theories be transformed into adequate mathematical models supported by relevant methods of statistical data analysis. With this in mind, the goal of this book is.