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Báo cáo Y học: The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168

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Campylobacter jejuniinfections are one of the leading causes of human gastroenteritis and are suspected of being a pre-cursor to Guillain–Barre´ and Miller–Fisher syndromes. Recently, the complete genome sequence ofC. jejuniNCTC 11168wasdescribed. In this study, themolecular structureof the lipooligosaccharide and capsular polysaccharide of C. jejuniNCTC 11168 was investigated. The lipooligosac-charide was shown to exhibit carbohydrate structures anal-ogous to the GM1a and GM2 carbohydrate epitopes of human gangliosides (shown below).

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