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Báo cáo khoa học: Pressure and heat inactivation of recombinant human acetylcholinesterase Importance of residue E202 for enzyme stability

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The effects of pressure on structure and activity of recom-binant human acetylcholinesterase (rHuAChE) were inves-tigatedup toapressureof 300 MPausinggel electrophoresis under elevated hydrostatic pressure, fluorescence of bound 8-anilinonaphthalene-1-sulfonate (ANS) and activity meas-urements followingexposure tohighpressure.

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