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Lecture Principles of biochemistry - Chapter 22 (part 2): Protein synthesis

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In this chapter, you will know the general structure of the ribosome (both prokaryotic and eukaryotic) (i.e. the 70 S prokaryotic ribosome is made up of the 30S and 50S ribosomal subunits. The 80S eukaryotic ribosome is made up of the 40S and 60S ribosomal subunits). Know that the large ribosomal subunits contain a “tunnel” through which the growing protein chain exits the ribosome. Know that the mRNA is associated with the small ribosomal subunit. Know the properties of the A-site, the P-site and the E-sites,. | Chapter 22 (Part 2) Protein Synthesis Ribosomes Prokaryotic Ribosome Structure Eukaryotic Ribosome Structure Ribosome Assembly Assembly is coupled w/ transcription and pre-rRNA processing Ribosome Structure Identification of Initiator Codon in Prokaryotes Prokaryotic Translational Initiation Eukaryotic Initiation of Translation Recycling of EF-Tu Peptide Bond formation Formation of Peptide Bond More on elongation Regulation of Gene Expression AAAAAA 5’CAP mRNA RNA Processing RNA Degradation Protein Degradation Post-translational modification Active enzyme Regulation of Globin gene translation by heme | Chapter 22 (Part 2) Protein Synthesis Ribosomes Prokaryotic Ribosome Structure Eukaryotic Ribosome Structure Ribosome Assembly Assembly is coupled w/ transcription and pre-rRNA processing Ribosome Structure Identification of Initiator Codon in Prokaryotes Prokaryotic Translational Initiation Eukaryotic Initiation of Translation Recycling of EF-Tu Peptide Bond formation Formation of Peptide Bond More on elongation Regulation of Gene Expression AAAAAA 5’CAP mRNA RNA Processing RNA Degradation Protein Degradation Post-translational modification Active enzyme Regulation of Globin gene translation by . | Chapter 22 (Part 2) Protein Synthesis Ribosomes Prokaryotic Ribosome Structure Eukaryotic Ribosome Structure Ribosome Assembly Assembly is coupled w/ transcription and pre-rRNA processing Ribosome Structure Identification of Initiator Codon in Prokaryotes Prokaryotic Translational Initiation Eukaryotic Initiation of Translation Recycling of EF-Tu Peptide Bond formation Formation of Peptide Bond More on elongation Regulation of Gene Expression AAAAAA 5’CAP mRNA RNA Processing RNA Degradation Protein Degradation Post-translational modification Active enzyme Regulation of Globin gene translation by heme | Chapter 22 (Part 2) Protein Synthesis Ribosomes Prokaryotic Ribosome Structure Eukaryotic Ribosome Structure Ribosome Assembly Assembly is coupled w/ transcription and pre-rRNA processing Ribosome Structure Identification of Initiator Codon in Prokaryotes Prokaryotic Translational Initiation Eukaryotic Initiation of Translation Recycling of EF-Tu Peptide Bond formation Formation of Peptide Bond More on elongation Regulation of Gene Expression AAAAAA 5’CAP mRNA RNA Processing RNA Degradation Protein Degradation Post-translational modification Active enzyme Regulation of Globin gene translation by . | Chapter 22 (Part 2) Protein Synthesis Ribosomes Prokaryotic Ribosome Structure Eukaryotic Ribosome Structure Ribosome Assembly Assembly is coupled w/ transcription and pre-rRNA processing Ribosome Structure Identification of Initiator Codon in Prokaryotes Prokaryotic Translational Initiation Eukaryotic Initiation of Translation Recycling of EF-Tu Peptide Bond formation Formation of Peptide Bond More on elongation Regulation of Gene Expression AAAAAA 5’CAP mRNA RNA Processing RNA Degradation Protein Degradation Post-translational modification Active enzyme Regulation of Globin gene translation by heme

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