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Comparison of the therapeutic efficacy of microwave ablation and radio-frequency ablation for hepatoccelular carcinomas

Objectives: Comparison of the therapeutic efficacy of percutaneous microwave ablation (MWA) and radio frequency ablation (RFA) for treatment of hepatocellular carcinomas (HCC). Subjects and method: 136 patients with HCC were divided into two groups. 66 patients with 71 tumors were treated with MWA and 70 with 74 tumors were treated with RFA. | Journal of military pharmaco-medicine no2-2018 COMPARISON OF THE THERAPEUTIC EFFICACY OF MICROWAVE ABLATION AND RADIO-FREQUENCY ABLATION FOR HEPATOCCELULAR CARCINOMAS Vo Hoi Trung Truc*; Tran Viet Tu** SUMMARY Objectives: Comparison of the therapeutic efficacy of percutaneous microwave ablation (MWA) and radio frequency ablation (RFA) for treatment of hepatocellular carcinomas (HCC). Subjects and method: 136 patients with HCC were divided into two groups. 66 patients with 71 tumors were treated with MWA and 70 with 74 tumors were treated with RFA. Results: The complete response rate of MWA and RFA were 95.7% and 97.3%, respectively. No significant differences in the complete response rate between modalities (MWA and RFA) and tumor sizes ( 2, venous thrombosis (portal vein, hepatic variables vein, lower vena cava), bile duct dilation, analyzed with the Chi-square test or distant metastasis or invasion of adjacent Fisher’s exact test and with student’s organs. t-test, between respectively, groups using Stata version A total of 136 eligible patients were signed-rank test is used when comparing enrolled in this prospective cohort study. two matched samples. DFS curve was Under the guidance of real-time ultrasound, evaluated using Kaplan-Meier curve and the antenna of the microwave system compared using the log-rank test. To AveCure (Medwaves, USA) or the electrode identify the prognostic factors for DFS, 12 of Valley-lab Cool-tip™ RF Ablation System variables were used, including ablation (Covidien, USA) was percutaneously probed modality (MWA/RFA), age (3 3/27/41 0.534 5/33/36 Mean ± SD 3.3 ± 1 0.573 3.2 ± 1 1/≥ 2 57/14 0.504 56/18 Mean ± SD 1.2 ± 0,4 0.220 1.3 ± 0.6 Nodule size (cm) Sessions for one nodule Complete response Overall 95.8% 97.3% Nodule ≤ 3 cm 97% 97.5% Nodule > 3 cm 94.6% 97.1% (n2: Total number of nodules) No significant differences in nodule sizes and the number of ablation sessions for the .