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The study on clinical characteristics and relationship between levels of depression and cranial MRI in patients with lacunar infarcts in supratentorial region

Objectives: To study clinical characteristics, and relationship between levels of depression and cranial MRI of patients with lacunar infarction. Subjects and methods: Cross-sectional study and self-design research questionnaire. | Journal of military pharmaco-medicine no5-2018 THE STUDY ON CLINICAL CHARACTERISTICS AND RELATIONSHIP BETWEEN LEVELS OF DEPRESSION AND CRANIAL MRI IN PATIENTS WITH LACUNAR INFARCTS IN SUPRATENTORIAL REGION Dang Viet Hung*; Nguyen Minh Hien**; Nguyen Tram Anh*** SUMMARY Objectives: To study clinical characteristics, and relationship between levels of depression and cranial MRI of patients with lacunar infarction. Subjects and methods: Cross-sectional study and self-design research questionnaire. A total of 90 patients with lacunar infarcts and signs of depression collected from Department of Neurology of Viet - Czech Friendship Hospital between March 2013 and May 2015. Results: The time of onset of lacunar infarction from 6 to 12 am accounted for 53.33%. Among onset symptoms in the majority of patients, hemiplegia accounted for 85.56%, and language disorders accounted for 55.56%, motor dysfunction accounted for 60%. Mild depression, moderate depression, severe depression accounted for 43.33%, 35.56%, and 21.11%, respectively. Locations of lacuna in internal capsule, gray matter, and temporal lobe have not been found to affect levels of depression in cerebral infarction. Frontal lobe damage increased the risk of severe depression by 7.31 times than that of mild depression and 5.81 times than that of moderate depression. Left cerebral hemisphere damage increased the risk of severe depression 4.88 times more than mild depression. Conclusion: There is no clear relationship between levels of depression and cranial MRI in patients with lacunar infarction. * Keywords: Lacunar infarction; Clinical characters; Level of depression; Cranial MRI. INTRODUCTION Stroke has become an increasingly important medical problem due to the average life increasing more and more, the stroke rates have increased according to the age. It is predicted that if there were 12.8% of Americans > 65 years had stroke in 1995, there would be 18.7% in 2025. Lacunar infarction, which accounts for .