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Protein 4.1B suppresses tumor metastasis by regulating epithelial–mesenchymal transition progression in melanoma cells

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Epithelial-mesenchymal transition (EMT), which involves the dramatic reorganization of the cytoskeleton, is a crucial initiating step in tumor invasion and metastasis. Protein 4.1B is a membrane-cytoskeleton cross-linker that plays an important role in tumor progression and metastasis; however, the functional roles of 4.1B in melanoma remain unclear. | Protein 4.1B suppresses tumor metastasis by regulating epithelial–mesenchymal transition progression in melanoma cells