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Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: A randomized, open-label, multiple dose, crossover study

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Triflusal is a drug that inhibits platelet aggregation. In this study we investigated the dose-exposureresponse relationship of a triflusal formulation by population pharmacokinetic (PK) and pharmacodynamic (PD) modeling of its main active metabolite, hydroxy-4-(trifluoromethyl) benzoic acid (HTB). | Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: A randomized, open-label, multiple dose, crossover study

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Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: A randomized, open-label, multiple dose, crossover study

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