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Rapid generation and selection of Cas9- engineering TRP53 R172P mice that do not have off-target effects

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Genetic mutations cause severe human diseases, and suitable animal models to study the regulatory mechanisms involved are required. The CRISPR/Cas9 system is a powerful, highly efficient and easily manipulated tool for genetic modifications. | Rapid generation and selection of Cas9- engineering TRP53 R172P mice that do not have off-target effects

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Rapid generation and selection of Cas9- engineering TRP53 R172P mice that do not have off-target effects
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