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Three smart spectrophotometric methods for resolution of severely overlapped binary mixture of Ibuprofen and Paracetamol in pharmaceutical dosage form

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Paracetamol is an analgesic-antipyretic drug and Ibuprofen is a non-steroidal anti-infammatory drug. They are coformulated as tablets to improve analgesia, to simplify prescribing and to improve patient compliance. Three accurate, simple and sensitive spectrophotometric methods were developed for the simultaneous determination of Paraceta‑ mol and Ibuprofen in their co-formulated dosage form. | Three smart spectrophotometric methods for resolution of severely overlapped binary mixture of Ibuprofen and Paracetamol in pharmaceutical dosage form