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Treatment-related changes in neuroendocrine tumors as assessed by textural features derived from 68GaDOTATOC PET/MRI with simultaneous acquisition of apparent diffusion coefficient

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Neuroendocrine tumors (NETs) frequently overexpress somatostatin receptors (SSTRs), which is the molecular basis for 68Ga-DOTATOC positron-emission tomography (PET) and radiopeptide therapy (PRRT). However, SSTR expression fluctuates and can be subject to treatment-related changes. | Treatment-related changes in neuroendocrine tumors as assessed by textural features derived from 68GaDOTATOC PET MRI with simultaneous acquisition of apparent diffusion coefficient