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Gene expression profile and cancerassociated pathways linked to progesterone receptor isoform a (PRA) predominance in transgenic mouse mammary glands

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Progesterone receptor (PR) is expressed from a single gene as two isoforms, PRA and PRB. In normal breast human tissue, PRA and PRB are expressed in equimolar ratios, but isoform ratio is altered during malignant progression, usually leading to high PRA:PRB ratios. | Gene expression profile and cancerassociated pathways linked to progesterone receptor isoform a PRA predominance in transgenic mouse mammary glands

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Gene expression profile and cancerassociated pathways linked to progesterone receptor isoform a (PRA) predominance in transgenic mouse mammary glands

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