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Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma

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PCDH10, one of the non-clustered protocadherins, is identified as a tumor suppressor gene in many tumors. Recently, promoter methylation of PCDH10 was found in diffuse large B-cell lymphoma (DLBCL) but not in normal lymph nodes, suggesting that its epigenetic aberrance is essential to the lymphomagenesis. | Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma

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