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Ovalbumin based microlasers

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In this work, biomaterial based microlasers were successfully fabricated by a cost effective, simple and environmental friendly method. The as-fabricated microlasers were made of biocompatible material including ovalbumin doped Rhodamine B at low weight percentage. | VNU Journal of Science Mathematics Physics Vol. 36 No. 2 2020 106-111 Original Article Ovalbumin Based Microlasers Hanh Hong Mai Faculty of Physics University of Science Vietnam National University 334 Nguyen Trai Thanh Xuan Hanoi Vietnam Received 02 April 2020 Revised 29 April 2020 Accepted 02 May 2020 Abstract In this work biomaterial based microlasers were successfully fabricated by a cost effective simple and environmental friendly method. The as-fabricated microlasers were made of biocompatible material including ovalbumin doped Rhodamine B at low weight percentage. The lasers are shaped as solid-state spheres with various diameters ranging from 20 µm to over 100 µm. It was shown that inside the spherical cavity which supported whispering gallery mode a lasing emission was generated with a low threshold of 17.5 µJ mm2 and a high Q-factor of approximately 3000. The remarkable lasing properties of the dye doped ovalbumin microlasers are considered as important bases for their future biological and medical applications. Keywords Microlasers ovalbumin whispering gallery mode. 1. Introduction Recently microlasers have drawn tremendous attention due to their wide range applications in biology and medicine 1 2 . For biological and medical applications biomaterials are preferably used fore both gain and laser cavity due to their biodegradable bioresorbable biocompatible and typically environmentally friendly properties 3 5 . Ovalbumin OVA is the major protein from egg white containing 54 m m of the total protein content 6 . OVA has been used in numerous optical electrical and medical applications. For example OVA is used in immunological studies as a carrier protein in vaccines and a model protein in egg sensitivity allergy tests 7 . In optical applications OVA is also a promising material due to its high solubility in aqueous media good optical transparency. Despite these excellent properties ovalbumin has been rarely investigated as an appropriate material for a .