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Study protocol of REGOSARC trial: Activity and safety of regorafenib in advanced soft tissue sarcoma: a multinational, randomized, placebo-controlled, phase II trial

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Angiogenesis, among other signaling pathways, plays a key-role in sarcoma biology. Regorafenib (RE) has recently been shown to be effective in imatinib and sunitinib-refractory GIST in a phase III trial. |

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Insight into bladder cancer care: Study protocol of a large nationwide prospective cohort study (BlaZIB)

A longitudinal investigation of the factors associated with increased RISk of playingrelated musculoskeletal disorders in MUsic students (RISMUS): A study protocol

Incidence and risk factors for poor ankle functional recovery, and the development and progression of posttraumatic ankle osteoarthritis after significant ankle ligament injury (SALI): The SALI cohort study protocol

NASCITA Italian birth cohort study: A study protocol

Longitudinal Evaluation of Transition Services (“LETS Study”): Protocol for outcome evaluation

Collaborative model of care between Orthopaedics and allied healthcare professionals in knee osteoarthritis (CONNACT): Study protocol for an effectiveness-implementation hybrid randomized control trial

Comparing two interdisciplinary occupational rehabilitation programs for employees on sick leave: A mixed-method design study protocol

The WIRE study a phase II, multi-arm, multicentre, non-randomised window-ofopportunity clinical trial platform using a Bayesian adaptive design for proof-ofmechanism of novel treatment strategies in operable renal cell cancer – a study protocol

Oncologic outcomes of single-incision laparoscopic surgery versus conventional laparoscopic surgery for colorectal cancer (CSILS): Study protocol for a multicentre, prospective, open-label, noninferiority, randomized controlled trial

The combined impact of LLINs, house screening, and pull-push technology for improved malaria control and livelihoods in rural Ethiopia: Study protocol for household randomised controlled trial
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