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Study protocol of the RAND-study: A multicenter, prospective cohort study investigating response and adherence to nilotinib treatment in chronic myeloid leukemia

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The antitumor drug nilotinib has a large inter- and intra individual variability in pharmacokinetics. Adherence to treatment may substantially influence plasma levels and has been recognized as the most important determinant of treatment failure in chronic myeloid leukemia (CML). |

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