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The effect of different dosing regimens of motesanib on the gallbladder: A randomized phase 1b study in patients with advanced solid tumors

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Gallbladder toxicity, including cholecystitis, has been reported with motesanib, an orally administered small-molecule antagonist of VEGFRs 1, 2 and 3; PDGFR; and Kit. We assessed effects of motesanib on gallbladder size and function. |

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