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AutoCryoPicker: An unsupervised learning approach for fully automated single particle picking in Cryo-EM images

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An important task of macromolecular structure determination by cryo-electron microscopy (cryo-EM) is the identification of single particles in micrographs (particle picking). Due to the necessity of human involvement in the process, current particle picking techniques are time consuming and often result in many false positives and negatives. |