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Mutational Signatures in Cancer (MuSiCa): A web application to implement mutational signatures analysis in cancer samples

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Mutational signatures have been proved as a valuable pattern in somatic genomics, mainly regarding cancer, with a potential application as a biomarker in clinical practice. Up to now, several bioinformatic packages to address this topic have been developed in different languages/platforms. |

TÀI LIỆU LIÊN QUAN

Mutational Signatures in Cancer (MuSiCa): A web application to implement mutational signatures analysis in cancer samples

SigProfilerMatrixGenerator: A tool for visualizing and exploring patterns of small mutational events

SigsPack, a package for cancer mutational signatures

Generating realistic null hypothesis of cancer mutational landscapes using SigProflerSimulator

Different mutational characteristics of the subsets of EGFR-tyrosine kinase inhibitor sensitizing mutation-positive lung adenocarcinoma

DeconstructSigs: Delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

Mutational landscape differences between young-onset and older-onset breast cancer patients

MutSpec: A Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes

Helmsman: Fast and efficient mutation signature analysis for massive sequencing datasets

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
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