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JACUSA: Site-specific identification of RNA editing events from replicate sequencing data

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RNA editing is a co-transcriptional modification that increases the molecular diversity, alters secondary structure and protein coding sequences by changing the sequence of transcripts. The most common RNA editing modification is the single base substitution (A → I) that is catalyzed by the members of the Adenosine deaminases that act on RNA (ADAR) family. |