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Early tissue responses to zoledronate, locally delivered by bone screw, into a compromised cancellous bone site: A pilot study

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In fracture treatment, adequate fixation of implants is crucial to long-term clinical performance. Bisphosphonates (BP), potent inhibitors of osteoclastic bone resorption, are known to increase peri-implant bone mass and accelerate primary fixation. However, adverse effects are associated with systemic use of BPs. |

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Early tissue responses to zoledronate, locally delivered by bone screw, into a compromised cancellous bone site: A pilot study

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