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ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-toGolgi traffic

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Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate this process. ULK1 phosphorylates a number of target proteins and regulates many cellular processes including the early secretory pathway. |