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Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells

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The thymus is a highly specialized organ of the immune system where T cell precursors develop and differentiate into self-tolerant CD4+ or CD8+ T cells. No studies to date have investigated how the human transcriptome profiles differ, between T cells still residing in the thymus and T cells in the periphery. |

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