Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

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Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

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The genomes of laboratory rat strains are characterised by a mosaic haplotype structure caused by their unique breeding history. These mosaic haplotypes have been recently mapped by extensive sequencing of key strains. Comparison of genomic variation between two closely related rat strains with different phenotypes has been proposed as an effective strategy for the discovery of candidate strain-specific regions involved in phenotypic differences. |

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Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

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Đang chuẩn bị liên kết để tải về tài liệu: Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat

Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome

Comprehensive evaluation of structural variation detection algorithms for whole genome sequencing

HUPAN: A pan-genome analysis pipeline for human genomes

Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations

Massive gene presence-absence variation shapes an open pan-genome in the Mediterranean mussel

Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure

Towards pan-genome read alignment to improve variation calling

Genome structure variation analyses of peach reveal population dynamics and a 1.67 Mb causal inversion for fruit shape

Cotton pan-genome retrieves the lost sequences and genes during domestication and selection

Đang chuẩn bị liên kết để tải về tài liệu:
Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat