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Nutrigenomics studies to explore antiaging: Drosophila approach

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The epigenetic mechanisms involved have also been explained to an extent. Certain diseases that manifest due to ageing can potentially be delayed with the right nutrition and diet. Antioxidants and polyphenols help reduce the oxidative stress, and this study is important as oxidative stress is one of the main reasons of ageing. Many theories for ageing have been hypothesised and are under study. Nutrigenomics might be the break-through that changes the perception of “diets” and how beneficial the right diet can be on human health. | NUTRIGENOMICS STUDIES TO EXPLORE ANTIAGING Drosophila APPROACH Vijaya Harini Sathyamurthy1a Indhuja Jayaraj1b Supriya Velraja2 and Deepa Parvathi Venkatachalam 1 Address es 1a Undergraduate Student Department of Biomedical Sciences Faculty of Biomedical Sciences and Technology Sri Ramachandra Institute of Higher Education and Research Porur Chennai 600116 India. 1b PhD Scholar Department of Biomedical Sciences Faculty of Biomedical Sciences and Technology Sri Ramachandra Institute of Higher Education and Research Porur Chennai 600116 India. 2 Assistant Professor Department of Clinical Nutrition Faculty of Allied Health Sciences Sri Ramachandra Institute of Higher Education and Research Porur Chennai 600116 India. 1 Assistant Professor Department of Biomedical Sciences Faculty of Biomedical Sciences and Technology Sri Ramachandra Institute of Higher Education and Research Porur Chennai 600116 India. Corresponding author deepaparvathi@sriramachandra.edu.in deepakoushik305@gmail.com https doi.org 10.15414 jmbfs.4814 ARTICLE INFO ABSTRACT Received 24. 5. 2021 The field of Nutrigenomics has always been of interest to scientists as it integrates the field of nutrition and the -omics . Drosophila Revised 1. 10. 2021 melanogaster is the most suitable model for this study as appx. 60 of human diseases have homology in flies. Ageing is a complex Accepted 8. 10. 2021 mechanism that involves several pathways and only a small fraction of these pathways has been studied in detail. There have been proofs Published xx.xx.201x that nutrition can extend or reduce life span. The epigenetic mechanisms involved have also been explained to an extent. Certain diseases that manifest due to ageing can potentially be delayed with the right nutrition and diet. Antioxidants and polyphenols help reduce the oxidative stress and this study is important as oxidative stress is one of the main reasons of ageing. Many theories for ageing have been Regular article hypothesised and are under study. .