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Deletion of soluble epoxide hydrolase attenuates mice Hyperoxic acute lung injury

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Recent studies reported that soluble epoxide hydrolase (sEH) plays an important role in lung diseases. However, the role of sEH in hyperoxia-induced ALI is unclear. Methods: ALI was induced by exposure to 100% oxygen in an airtight cage for 72 h in wild-type (WT) and sEH gene deletion (EPHX2−/− ) mice. |

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