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Development of a scalable extraction protocol for recovery of tetrodotoxin from pufferfish viscera

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Tetrodotoxin analogues (TTXs) have been broadly applied in many fields. Viscera of pufferfish from Viet Nam was reported to contain a high level of TTXs, indicating a promising source for isolation of TTXs. In this work, critical factors affecting TTX recovery yield from pufferfish viscera collected from fishermen in the Can Gio coast of Viet Nam were optimized using response surface methodology (RSM). |

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