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Synthesis, characterization and anticancer activity of Ni(II), Cu(II), Pd(II) and Au(III) complexes derived from novel Mannich base

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This compound converted to Mannich base which interne illustrated as tridentate ligand of NO2-type. Meanwhile, the organic synthesis of the compounds is not an easy task, especially lactonization; hint naphthafuran-2-one has never been prepared from amino nitrile previously. Selected metal ions of known anticancer activity interacted with the ligand to present novel complexes to figure out the cytotoxicity effect of both organic and inorganic parts against cancer cell line. |

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