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Báo cáo y học: " Role of Dietary Soy Protein in Obesity"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Role of Dietary Soy Protein in Obesity. | Int. J. Med. Sci. 2007 4 72 International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2007 4 2 72-82 Ivyspring International Publisher. All rights reserved Review Role of Dietary Soy Protein in Obesity Manuel T. Velasquez1 and Sam J. Bhathena1 2 1. Department of Medicine George Washington University Medical Center Washington DC USA 2. Phytonutrients Laboratory Beltsville Human Nutrition Research Center Agricultural Research Service U.S. Department of Agriculture Beltsville Maryland USA Correspondence to Dr. Sam J. Bhathena Phytonutrients Laboratory Beltsville Human Nutrition Center Bldg. 307-C Rm 215 Beltsville MD 20705 USA. Received 2006.12.05 Accepted 2007.02.25 Published 2007.02.26 Soy protein is an important component of soybeans and provides an abundant source of dietary protein. Among the dietary proteins soy protein is considered a complete protein in that it contains ample amounts of all the essential amino acids plus several other macronutrients with a nutritional value roughly equivalent to that of animal protein of high biological value. Soy protein is unique among the plant-based proteins because it is associated with isoflavones a group of compounds with a variety of biological properties that may potentially benefit human health. An increasing body of literature suggests that soy protein and its isoflavones may have a beneficial role in obesity. Several nutritional intervention studies in animals and humans indicate that consumption of soy protein reduces body weight and fat mass in addition to lowering plasma cholesterol and triglycerides. In animal models of obesity soy protein ingestion limits or reduces body fat accumulation and improves insulin resistance the hallmark of human obesity. In obese humans dietary soy protein also reduces body weight and body fat mass in addition to reducing plasma lipids. Several potential mechanisms whereby soy protein may improve insulin resistance and lower body fat and blood lipids are discussed and