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Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depression. | Int. J. Med. Sci. 2010 7 224 International Journal of Medical Sciences 2010 7 4 224-231 Ivyspring International Publisher. All rights reserved Research Paper Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depression Wei HE 1.2 Hao CHAI 1.2 Yingchun ZHANG 1 Shaohua YU 2 3 Wei CHEN 1 and Wei WANG 1 2 H 1. Department of Psychiatry Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou China 2. Department of Clinical Psychology and Psychiatry Zhejiang University School of Medicine Hangzhou China 3. Department of Psychiatry Second Hospital Zhejiang University School of Medicine Hangzhou China H Corresponding author Dr. Wei WANG B.Med. D.Sc. Department of Clinical Psychology and Psychiatry Zhejiang University School of Medicine Yuhangtang Road 388 Hangzhou Zhejiang 310058 China Tel 86-571-88208188. Email wangmufan@msn.com or DrWang@Doctor.com Received 2010.04.06 Accepted 2010.06.29 Published 2010.07.02 Abstract Background and Objectives The line bisection error to the left of the true center has been interpreted as a relative right hemisphere activation which might relate to the subject s emotional state. Considering that patients with generalized anxiety disorder GAD or treatment-resistant depression TRD often have negative emotions we hypothesized that these patients would bisect lines significantly leftward. Methods We tried the line bisection task in the right-handed healthy volunteers n 56 GAD n 47 and TRD outpatients n 52 . Subjects also completed the Zuckerman - Kuhlman Personality Questionnaire the Zuckerman Sensation Seeking Scales and the Plutchik-van Praag Depression Inventory. Results GAD patients scored highest on the Neuroticism-Anxiety trait TRD patients scored highest on depression and both patients scored lower on the Sociability trait. Patients with GAD also bisected lines significantly leftward compared to the healthy subjects. The Frequency of the bisection error was negatively .