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Báo cáo y học: "Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports."

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports. | Pelizza et al. Annals of General Psychiatry 2010 9 12 http www.annals-general-psychiatry.eom content 9 1 12 ANNALS OF GENERAL PSYCHIATRY CASE REPORT Open Access Psychiatric disorder as clinical presentation of primary Sjogren s syndrome two case reports Lorenzo Pelizza Federica Bonacini Alberto Ferrari Abstract Psychiatric disorders in primary Sjogren s syndrome constitute a possible clinical reality that each practitioner must be able to recognise and treat. In this article two case reports of mental disorder as clinical presentation of primary Sjogren s syndrome are presented suggesting that psychiatric manifestations in primary Sjogren s syndrome can occur not only during its longitudinal course but also at the onset of the autoimmune syndrome. A better adapted prescription of corticosteroids and or immunosuppressive agents together with specific psychotropic treatments can induce rapid relief of mental symptoms. Background Sjogren s syndrome SS is considered to be one of the most common autoimmune diseases with a prevalence thought to equal or exceed that of rheumatoid arthritis 2 to 4 of the population 1 . It is characterised by a chronic inflammation of the lachrymal and salivary glands which leads to exocrine hypofunction and the well recognised clinical features of dry eyes xerophthalmia and dry mouth xerostomia . Other exocrine glands may also be affected causing a wider variety of complaints for example cough pancreatic insufficiency chronic sinusitis gingivitis and laryngitis . In isolation SS is termed primary and when in combination with another autoimmune disease such as systemic lupus erythematosus SLE or rheumatoid arthritis RA it is termed secondary . The distinction between secondary and primary SS is difficult and a source of debate in the rheumatological literature. However there seems to be a moderate specificity of different types of anti-nuclear antibodies ANA for different rheumatolo-gical illnesses. In 50 to 80 of patients with SS anti-Ro .