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Báo cáo khoa học: "Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive ductal carcinoma"

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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive ductal carcinoma | World Journal of Surgical Oncology BioMed Central Research Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive ductal carcinoma James W Horvath1 Gary E Barnett1 Rafael E Jimenez1 Donn C Young2 and Stephen P Povoski 3 Open Access Address Department of Pathology The Ohio State University Columbus Ohio 43210 USA 2Center for Biostatistics The Ohio State University Columbus Ohio 43210 USA and 3Division of Surgical Oncology Department of Surgery Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and Comprehensive Cancer Center The Ohio State University Columbus Ohio 43210 USA Email James W Horvath - james.horvath@osumc.edu Gary E Barnett - gary.barnett@osumc.edu Rafael E Jimenez - Jimenez.Rafael@mayo.edu Donn C Young - young.7@osu.edu Stephen P Povoski - stephen.povoski@osumc.edu Corresponding author Published 24 March 2009 Received 21 December 2008 __I 10 11 All 7010 1 u Accepted 24 March 2009 World Journal of Surgical Oncology 2009 7 34 doi l0.ll86 l477-78l9-7-34 This article is available from http www.wjso.cOm content 7 l 34 2009 Horvath et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Sentinel lymph node SLN biopsy is the standard of care for the surgical assessment of the axilla during breast cancer surgery. However the diagnostic accuracy of intraoperative frozen section analysis for confirming metastatic involvement of SLNs in cases of invasive lobular carcinoma ILC versus that of invasive ductal carcinoma IDC has generated controversy secondary to a frequently low-grade cytologic appearance and an often discohesive pattern displayed by metastatic lymph nodes in ILC. In

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