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Báo cáo khoa học: "Treatment of early uterine sarcomas: disentangling adjuvant modalities"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Treatment of early uterine sarcomas: disentangling adjuvant modalities | World Journal of Surgical Oncology BioMed Central Open Access Treatment of early uterine sarcomas disentangling adjuvant modalities Flora Zagouri1 Athanasios-Meletios Dimopoulos1 Stelios Fotiou2 Vassilios Kouloulias3 and Christos A Papadimitriou 1 Address Department of Clinical Therapeutics Alexandra Hospital University of Athens School of Medicine Athens Greece 2Aretaieion Hospital University of Athens School of Medicine Athens Greece and 3Attikon Hospital University of Athens School of Medicine Athens Greece Email Flora Zagouri - florazagouri@yahoo.co.uk Athanasios-Meletios Dimopoulos - mdimop@med.uoa.gr Stelios Fotiou - sfotiou@yahoo.gr Vassilios Kouloulias - vkoul@yahoo.gr Christos A Papadimitriou - chr_papadim@yahoo.gr Corresponding author Published 8 April 2009 Received 5 November 2008 World Journal of Surgical Oncology 2009 7 38 doi 10.1186 1477-7819-7-38 Accepted 8 April 2009 This article is available from http www.wjso.cOm content 7 1 38 2009 Zagouri et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Uterine sarcomas are a rare group of neoplasms with aggressive clinical course and poor prognosis. They are classified into four main histological subtypes in order of decreasing incidence carcinosarcomas leiomyosarcomas endometrial stromal sarcomas and other sarcomas. The pathological subtype demands a tailored approach. Surgical resection is regarded as the mainstay of treatment. Total abdominal hysterectomy and bilateral salpingo-oophorectomy represents the standard treatment of uterine sarcomas. Pelvic and para-aortic lymph node dissection in carcinosarcomas is recommended given their high incidence of lymph node metastases and may have a role in endometrial stromal sarcomas. Adjuvant radiation therapy