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Báo cáo khoa học: " Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose-volume analysis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy: a dose-volume analysis. | Radiation Oncology BioMed Central Research Comparison of rectal volume definition techniques and their influence on rectal toxicity in patients with prostate cancer treated with 3D conformal radiotherapy a dose-volume analysis Cem Onal Erkan Topkant Esma Efe Melek Yavuzt Serhat Sonmezt and Aydin Yavuzt Address Department of Radiation Oncology Baskent University Medical Faculty Adana Turkey Email Cem Onal - hcemonal@hotmail.com Erkan Topkan - drerkantopkan@yahoo.com Esma Efe - efeesma@gmail.com Melek Yavuz - mayvuz@baskent-adn.edu.tr Serhat Sonmez - serhatsnmzy@yahoo.com Aydin Yavuz - ayavuz@baskent-adn.edu.tr Corresponding author tEqual contributors Open Access Published II May 2009 Received 17 February 2009 Radiation Oncology 2009 4 14 doi 10.1186 1748-717X-4-14 Accepted 1 1 May 2009 This article is available from http www.ro-journal.com content 4 I I4 2009 Onal et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background To evaluate the impact of four different rectum contouring techniques and rectal toxicities in patients with treated with 3D conformal radiotherapy 3DCRT . Methods Clinical and dosimetric data were evaluated for 94 patients who received a total dose 3DCRT of 70 Gy and rectal doses were compared in four different rectal contouring techniques the prostate-containing CT sections method 1 1 cm above and below the planning target volume PTV method 2 110 mm starting from the anal verge method 3 and from the anal verge to the sigmoid flexure method 4 . The percentage of rectal volume receiving RT doses 30-70 Gy and minimum mean rectal doses were assessed. Results Median age was 69 years. Percentage of rectal .